No. Call-only ads and call extensions lead to a phone call straight from Google's search results instead of a visit to your website, so there's no click for ClickGuard to track or analyze. ClickGuard can't protect them, but it keeps protecting your Search, Display and other campaigns in the same account.
No. ClickGuard doesn't support Call-only ads and call extensions.
Call-only ads are designed to result in calls made directly from Google's search result page, as opposed to search or display ads, where the ad impression results in a click. The same goes for call-only extensions, as they offer the same click-to-call functionality for call-ready devices (e.g. smartphones).
While ClickGuard can track and process ad clicks, the system cannot track calls, as the data available upon clicks (e.g. IP address) is not obtainable during phone calls. Without actionable data, the system is unable to perform campaign optimizations. Therefore, ClickGuard's optimization tools do not support call-only ads and extensions.
See also: Google Ads clicks not showing in ClickGuard.